Protectotype

 Dr Abhishek Pandey , Dr E Vijayakumar , Dr Raj trivedi

Concept and Features

• Development of Protectotype: Breadth of protection of the respiratory tract provided by different live-attenuated Infectious Bronchitis vaccines against challenge with IBV of heterologous serotypes cook, J-KA, etal- Avian Pathology -IWJ28;477-485

• Protectotype goes over serotypes: The concept of Protectotype, which from a practical point of view is more relevant than serotypes, shows that in vivo protection is much broader than the result of in vitro testing Rik. Globaltechnical Director MSD Animal Health

• Cross-protection and managing. variant viruses: A lot of research has been conducted on the protective ability of different IBV vaccines or combinations of IBV vaccine types. In general, using more than one type of IBV vaccine in a vaccine program will provide broader protection than the use of just one type of IBV vaccine. Mar*W.Jackwood, PhD. Poultry Health Tcday-2016

• Practica/IBContro/: In many countries, you have three, four, five variants. We’re realizing that it may be futile to vaccinate against one specific 1B virus strain. You have to try and make smart vaccine combinations, so your protection is broader. sjaak De PHD. The Poultry Site – 20121

Protectotype Advantages

• Unique Immunogenicity
• Predictable Behavior & Genetic Stability:
• Unparallel Performance : Protection against Major IBV strains present in the field conditions
• Breakthrough MDA+.’ can breakthrough high Maternally Derived Antibodies Level, yet SAFE in Low MDAs level.
• Safety at Hatchery Administration
• Safety on Field Administration (No Reversal to virulence)

Protectotype Performance

• Safety:
  • Hatchery:
    • Safe in baby chicks with low or high level of MDAs.
  • Field Administration:
    • No Significant Post Vaccinial Reaction.
    • During lay, does not produce any adverse systemic or reproductive vaccination reactions.
• Efficacy:
  • Respiratory protection
• Proven ciliostasis protection

• Kidney protection
  • Superior kidney protection (Colonization) against nephro-pathogenic IBV
  • Shows dominance for up to 8 weeks in kidneys without any lesions, reflecting on strong kidney protection.

Unique features:

• Genetic Stability:
  • Extremely consistent.
• Hiqhly Persistent:
  • Proven Persistence in the field establishes itself as the dominant vaccine strain on farm.